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Serena Williams and the Celebrity Ozempic Obsession: Why Everyone’s Injecting Hope (And Maybe Regret

Serena Williams and the Celebrity Ozempic Obsession: Why Everyone’s Injecting Hope (And Maybe Regret
  • PublishedAugust 24, 2025

Let’s be real—when Serena Williams drops a bombshell, it hits harder than her backhand. And yet here we are, not surprised in the least that even tennis royalty is now tangled up in the Ozempic craze. Because of course she is. Nothing says “progress” like watching multimillionaires inject themselves with diabetes meds to lose weight while the rest of us can’t afford groceries without side-eye from our bank accounts.

Welcome to my world, where every headline feels like a slow-motion car crash wrapped in glitter. I’m Sage Matthews, your reluctant tour guide through this dumpster fire of celebrity wellness culture, and yes—I’ve already poured myself a drink.

Serena recently confirmed what many had speculated: she’s been on GLP-1 drugs—Ozempic, Wegovy, you know the drill—and lost 31 pounds doing it. She shared the news on the Today show with all the enthusiasm of someone trying to sell you on why prison food is actually gourmet. But hey, at least she’s being honest about it. That’s more than we can say for half the red carpet crowd.

“I thought it was really important for me to come out and say it,” Serena said, as if confessing to a crime she didn’t commit but still wants credit for surviving. The goal? To destigmatize these medications. Which is noble. Also hilarious. Because nothing says “let’s normalize this” like having your husband invest in Ro, the very company prescribing your meds. Smooth move, Serena. Real grassroots activism.

She struggled to lose weight after having kids, which, again—no shade, but welcome to motherhood. She trained five hours a day and still couldn’t drop below a certain number on the scale. So she tried the drugs. And surprise, surprise—it worked. Not because she suddenly discovered magic, but because pharmaceuticals do things. Who knew?

But let’s give her credit where it’s due: she didn’t do it for looks. Or so she says. “I’ve never felt that pressure to maintain a certain appearance,” she told People. Sure, Serena. And I’m the Queen of England. Either way, she claims it made her feel better physically. Less joint pain, less discomfort. Fair enough. If popping a pen makes you feel human again, who am I to judge?

Of course, she’s not alone. Rosie O’Donnell has been on Mounjaro since late 2022 and posted a dramatic transformation photo on Instagram with the caption, “#mounjaro #weightloss #bodydismorphia.” Because nothing screams body positivity like hashtagging your injection journey like it’s a vacation postcard.

Meghan Trainor and Daryl Sabara took the couple goals thing to a new level by both starting low-dose Mounjaro together. After crushing the 75 Hard challenge—which sounds like something Bear Grylls would reject for being too intense—they decided to join the injection cult alongside their friends and doctors. Teamwork makes the dream work, right?

Then there’s Kendra Wilkinson, former Playboy star turned cautionary tale. She tried one shot of an unnamed drug and immediately threw the rest away. “Heard too many horror stories around me,” she explained. “People end up in ER. Surgeries. No thanks.” Bless her heart. One injection and she’s done. That’s commitment—or sheer terror. Either way, points for honesty.

And let’s not forget the Golden Globes host who defended Ozempic usage earlier this year, calling for more open-mindedness toward the drugs. Because heaven forbid we treat them like the miracle-and-mess hybrid they clearly are.

So what’s next? Probably a reality show where celebrities compete to see who can stay on the drugs the longest before needing emergency surgery. Or maybe just another round of headlines where someone else “accidentally” loses 40 pounds overnight and swears it’s just “clean eating and manifestation.”

In the meantime, I’ll be over here shaking my head and muttering, “Of course this happened.”

Sources: Celebrity Storm and People Magazine, E! Online
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Written By
Sage Matthews

Sage Matthews is a creative journalist who brings a unique and thoughtful voice to the world of celebrity news. With a keen eye for trends and a deep appreciation for pop culture, Sage crafts stories that are both insightful and engaging. Known for their calm and collected demeanor, they have a way of bringing clarity to even the messiest celebrity scandals. Outside of writing, Sage is passionate about environmental sustainability, photography, and exploring new creative outlets. They use their platform to advocate for diversity, inclusivity, and meaningful change in the media landscape.