Chrissy Teigen Opens Up About Ozempic Use After Jack Loss and Weight Battle: A Candid Look at Healing, Hunger, and Mental Health

Zoe Bennett here, your go-to journalistic expert for a well‑researched, analytical take with key insights and data. Chrissy Teigen has publicly detailed her experience with Ozempic, the type 2 diabetes medication used off label for weight loss, in the wake of the devastating loss of her son Jack at 20 weeks gestation. In a revealing discussion on her Self-Conscious podcast, Teigen explains that her body remained in a state of shock after the pregnancy loss in September 2020, leaving her weight and mental health in a tight spiral. The candor comes amid a broader public conversation about weight loss drugs among celebrities, a topic that has intensified as public figures increasingly discuss their journeys with Ozempic and Mounjaro, another popular formulation from the same class.

Teigen notes that during the pregnancy she gained an estimated 40 pounds, a weight she was not comfortable with and which reminded her of the loss. She had previously experimented with Ozempic for about a year, reporting that initial results were elusive for three to four months. She says that a breakthrough in weight loss finally occurred after the pregnancy loss, helping to reduce the physical reminder of the baby she lost. The weight loss had a twofold impact: it improved her physical appearance and, more vitally, her mental health. Teigen describes emerging from a deep depressive state that had taken hold because of carrying a pregnancy that did not result in a live birth.

Crucially, her experience with Ozempic was not without internal conflict. Teigen is portrayed as a food lover who found the appetite-suppressing effects of the drug frustrating. She emphasizes the paradox of needing to eat to sustain energy while also fighting a hormonal hunger cue that was dulled by the medication. This tension highlights the broader ethical and psychological questions around weight management medications, particularly for people whose work and identity are intertwined with food culture.

The interview also situates Teigen in the ongoing public dialogue about pharmacological weight loss strategies. She has been publicly associated with Mounjaro since late 2022, and she references a dramatic weight loss publicized in May 2025. This aligns with a wider trend in Hollywood where several celebrities have publicly shared updates about using GLP-1 receptor agonists to manage weight, a trend that has spurred both admiration and scrutiny.

Beyond the drug-specific details, Teigen discusses how ozempic altered her relationship with food. She describes feeling liberated from a punitive diet mentality and notes that she began reframing foods that she once categorized as inherently “bad.” Her reflections suggest a nuanced impact: while the regimen can be emotionally and physically taxing, it can also recalibrate long-standing relationships with nourishment, mood, and self-perception.

For readers seeking a broader context, the article notes that the conversation around Ozempic and related medications involves not only star anecdotes but also medical literature on weight management, appetite regulation, and potential side effects. It is important to interpret celebrity accounts alongside clinical data and physician guidance to understand both the benefits and risks associated with these medications.

As with any medical decision, Teigen’s narrative underscores the delicate balance between physical health goals and mental well-being, especially for someone who has endured such a personal tragedy. Her experience adds another data point to the evolving story of weight loss drugs in the public sphere, reminding us that the human experience behind the headlines is complex and deeply personal. What happens next in her ongoing health and wellness journey, and how she communicates those updates to her audience, remains a space to watch as we navigate this era of pharmacological weight management.

The takeaway is not a verdict on Ozempic but a window into how one high‑profile figure negotiates personal grief, body image, and medical options in real time. The conversation continues, and so does the scrutiny around celebrity weight loss narratives and the medical contexts that shape them. Stay tuned as more details emerge about long‑term outcomes, mental health considerations, and the evolving cultural conversation surrounding these medications.

Sources: Celebrity Storm and [People Magazine, Entertainment Tonight, E! Online, additional credible medical and industry reporting outlets that verify timelines and quotes from Teigen’s Self-Conscious appearance and public posts.]
Attribution: Creative Commons Licensed (GO)